The usual dosage of hydroxyzine for dogs is 1 mg per pound of body weight given two to three times per day. My dog was prescribed this to help stop the itch for her mysterious skin infection / bacteria ( that the vet could not tell what it was after paying over $500.00). He has been on Prednisone since he was 10. In addition, many kinds of research shows that CBD enhances the effects of chemo and fights cancer more efficiently! Dogs are able to take hydroxyzine. if taken off at all for one day she would lose all her hair in clumps and have sores all over where she licked or bit or scratched. My poodle is masterful at holding it in emergencies when we get home longer than planned. I feel apoquel has destroyed his ability to fight infections as before Ollie always responded well to treatments and now not at all. I will also take my other boy off this medication. Let these people talk about what they think about this drug. However, I decided not to renew the script and I am currently looking for a cure for the problem, not a way to mask the symptoms with dangerous chemicals. Her stays showed fluid in her heart area and fluid in her lungs. This morning at 5am, I took Peatie out for his early morning peepee and in a rain storm, he dropped on the sidewalk and seized upin a puddle of water on the cold sidewalk, my best friend had completely lost control of all bodily functions. I would say that these veterinarians are concerned about their wallets Last week I took her off the Apoquel, out of nowhere she started eating again, even playing and drinking water. P.S. Does zonisamide interact with my other drugs? I am convinced that apoquel is the cause and I would like to know if his liver enzymes will return to normal now that apoquel has been stopped. require discontinuation of therapy. Dr Jones. These include the severity of the symptoms, the size of your dog, and any existing treatments or illnesses your dog has. dog? As I write this my 4 month old puppy is in ICU getting I.V. Apoquel is approved for use in dogs 12 months and older. On February 15, 2018, Aries was back at the center with same issue and again a Rx issued for 70 Apoquel 5.4mg tabs with a charge of $138.60. Our girl is a 14 pound Yorkipoo. My 10 year old Italian Greyhound a rescue from a puppy mill in Nebraska was just diagnosed with liver cancer. Im not one to complain but, I feel compelled to share our nightmarish experience with this new anti-itching drug called Apoquel. by day 14. He takes 16 mg. daily and the scratching has almost stopped. I am pretty sure her seizures are tied in with a build up of Apoquel but its impossible to be sure. Zyrtec, or Cetirizine, is a popular method of itch relief in our canine friends due to how few side effects there are, and the fact that Zyrtec does not cause drowsiness like other allergy medications. This was very traumatic to witness in a 200 lb.dog. I wouldnt recommend it after our issues with it and reading others comments. We are stopping the med and taking to vet tomorrow to have full blood work done. Apoquel has made my dog awfully ill. We have spent so much money from the side effects of apoquel. Im going to bed. The night of the 21st I hand fed him ice chips in hopes to prevent dehydration. Apoquel is NOT worth the risk if Shortys symptoms are mild. Puppy was briefly having loose stool and some vomiting cleared up w/Flagyl- metronizone. She told me not to take the 2 bp meds and antistroke meds the traditional vet prescribes that diagnoses the kidney problem. I am certain that Apoquel caused this problem. She cant even find her toys unless I put them in her mouth. It worked amazing for my golden retriever she was constantly chewing her paws & itching all the time I hated the to think she would have to take a perscription meds for the rest of her life & then I tried it! It really seemed to help with the hacking and coughing and all. Fourth Quarter 2014 Reported Net Income of $126 Million, or $0.25 per Diluted Share, Increased 20% and 19%, respectively The internist believes that continuing the Apoquel any further (would) wreak havoc in his immune system, that we can only expect more papilloma lesions, further inflammation of his lymph nodes, lower platelet cell cell count and so on.". One of the advantages of the oral treatment Apoquel is that it's nonsteroidal and takes effect quickly. Sometimes he didnt even realize that he was urinating. eat, no appetite, and started throwing up. My 11 Yorkie mix has had allergiesitchy feet mostly but all over at times, that we have tolerated as holisticly as possible his whole lifewith the occasional Benadryl. Monitor your dog for any symptoms. Stopped giving it to her and in 48 hours, she is spunky again. WBC elevated, slight temperature, abdomen tender to touch and very dehydrated. The Prozac after three weeks did nothing, his shaking and breathing became worse. He continues to take 1 pill each day, although we have . No way will I us it.Thank you every one for opening my eyes. Nothing major, but different. Nowhere in the FDA stats on Apoquel does it claim that Apoquel is suppressing the immune system, and this caused pneumonia, mange, skin infection, bladder infection. I also wonder if advantix 2 would be responsible for his rash. Great! We brought him back to the vet on July 11, 2017 to evaluate at which time an antibiotic was prescribed and again a new prescription for 70 Apoquel 5.4mg tablets at a cost of $126.00 for the Apoquel. I still use the same vets but now use a different vet who we use exclusively so she is aware of my boys issues. Any advice????? He has also been drinking excessively since we started him on the drug and peeing in the house as well. Of course the cost is skyrocketing and he is scheduled to have a liver Ultrasound today and a liver fine needle aspiration has been mentioned. At the onset of all this she started behaving very depressed. I should have switched him to the prednisone after his ACL surgery but didnt think about it and didnt know that he had this tumor. no more for Her, and a new vet , too !! keep me up all night and day biting,scratiching licking she is a happy dog. He is aware of the harmful side effects of prescription drugs and is trying to give us healthier alternatives for our loving pets. Denise. Several dogs have passed, and she has several that she is not sure if they will not die they are so sick. If Cytopoint and Apoquel are going to be effective in a particular dog, they typically begin to work within the first 24 hours but may take a little longer to reach peak efficacy. Bald from chewing, scratching bleeding, pus coming out of his eyes and chronic ear infections, bad yeast odor. doubted that Apoquel was the cause. I am looking for suggestions on what to do. The kennel called and said she had a 2 min. It was a blistery, painful looking infection. Even when it was off the market, I had a doctor who had a source for me to continue getting the drug. Can you give a dog Zyrtec and Apoquel together? They vary from mild to severe. I called the vet but they said she must have eaten something to cause it. Is it okay to take her off immediately, or do I need to wean her gradually? Hard to articulate, more a pet parents knowing. I was suspect of this drug before I read the study. I blame this drug. Carprofen is a non-steroidal anti-inflammatory drug (NSAID) that is used by veterinarians as a supportive treatment for the relief of arthritic symptoms in geriatric dogs. He still has the runs. When I do find him upstairs he is comatose and has vomited all around the house and done a poo in the family room. Horrible diarrhea that even woke me up because she was frantic to get out in the middle of the nightalong with accidents of that nature, as well as the pee in the back bedroom.. (thank goodness we have hardwood floors). We purchased a bottle with 70 tablets for $137.20 in hopes that this would provide some relief. I took him back off of it and I called the vet and I said that I want to put him back on the pred. Im just sick. My husband took him to the Vet for his routine checkup on June 16th, he got a clean bill of health as usual. He also gets half a Zyrtec morning and night. She has been on 3 primary seizure drugs used in humans for almost a year now. Also, the little guy was not scratching. Eating and drinking well but started soiling in the house. I took my 58# My 6 y/o German shepherd was on this drug for approximately 8 weeks and is now deceased. He is a different dog entirely now that his life isnt consumed by itchiness and chewing and scratching. I hope you dont still practice medicine. (possibly why her bed was wet on days 19 and 21 too) I was aware of the risks involved with this drug and was well informed both by my vet and also by my own research before beginning his treatment. Apoquel wont work for my pin , her itching decreased, but never stopped, and it has side effects. I thought I had found the magic drug. We adopted this puppy from the Animal Defense League 2/16/2016. Our dog, Casey, 15.5 years old ,bishon, has severe allergy problems. Lately I have been trying Vitamin C which has some antihistamine qualities, and his itching is decreasing. Apoquel tablets for dogs comes strengths of 3.6mg, 5.4 mg and 16mg of oclacitinib per tablet. On the FDA report you wrote of earlier, Apoquels side effects arent listed only their FDA approvals are there. I thought it was due to me not being able to have play time (because of major surgery I had). They have been developed so as not to cause drowsiness. THIS DRUG KILLED MY DOG. The rate of adverse events overall was low (<5%) and included She also acts like she can see something that gets her attention and stares for ages. 6.Probiotics are increasingly being used for dogs with allergies. WSU is the leader in identifying drugs that may be dangerous for dogs with the MDR1 mutation and can identify alternative medications and doses. This is where we get our information. United States which showed that APOQUEL was effective in the treatment of pruritus Its not a perfect answer, but with some experimentation this drug is helping us keep him comfortable and from blowing up and getting infected areas. He is still on hepaticlear..3 years later. It especially targets the immune system. My question is whether there is any relationship between the Apoquel and tremors. and my dog was also very unstable and had trouble walking when on Apoquel. She runs into everything and everyone. We tried Benadryl, Temaril-P & homeopathic remedies. Im just heartbroken and will have to live with this guilt the rest of my life. To all dog owners WARNING do not give your dog Apoquel . Am wondering, Kelly, if you ever got any answers? She sent us to a vet that is a dermatologist 3 hours drive away. My 2 1/2 year old French Bulldog, Philippe, has been on Apoquel for a few months. The apoquel worked so well that I tried going down to smallest possible dose. I blame myself because I should have not let my guard down, I was naive to trust the doctor, how was I going to think that an allergy pill was going to kill my doggie. One morning I got up and he was shaking in his cage and couldnt lift his head. Not taking any chances! I took her to a vet here in Maine that I trust, The vet that prescribed the Apoquel was in Italy, and we did blood work. To the author..nice try, but no matter what your lab results showed, it seems the public test runs have proved otherwise. My shihtzu was dealing with itchy skin issues which we thought was a fungal infection. Stupid meI passed it off as a fluke. I just think until you have an allergic dog, you are unaware how wide spread of a problem it is. She went on this medication because she got extremely itchy from going into the lake. He seemed confused and his coordination was way off. If your dog vomits after taking Apoquel , try giving it with some food or a meal after consulting with your vet. http://www.fda.gov/AnimalVeterinary/SafetyHealth/ProductSafetyInformation/ucm055369.htm. I guess I need to do some more research. By then I had seen this and I pulled him off the apoquel and started him on benadryl. I have since taken her off of the pills and I can already see that her weight has gone down. Carprofen was previously used in human medicine for over 10 years (1985-1995). I have a 5 yr old Yorkie/Poodle. She has now had two seizures. This is because your vet will be able to advise you on the best course of action for your dog based on their individual health and medical history. so I went back to my regular vet I trusted who pit Ollie on ever increasing steroids to try to kill this yeast infection. Just choose your cases and decide if the medication risks outweigh the benefits. We have to be careful sometimes we give this drug because it eases our mind about our dog itching and being uncomfortable . But it is not the only antihistamine that vets use. Ive been looking for others with the same diagnosis. I am going to take him back m to the vet but I think I will try antihistamines and other supplements. As I write this I just want everyone to know.the drug may stop the itching as it did with my dog, but it allows the immune system to weaken and your dog wont be able to fight off the most basic thing: fungus. The dose of Apoquel is 0.18 to 0.27mg depending on the body weight of your dog. The omega 3 dose I suggest is 1000 mg per 10lbs daily- this works out to giving 1 tablespoon of flax per 50lbs daily to your dog. The vet took blood and urine. As with any medication, its always best to start with the lowest possible dose and increase gradually if necessary. My 4 year old Yorkie was put on apoquel. The first month he took the full dose of 5.4, the second month we halved it. For the most part hes back to being our happy, playful puppy. The vet gave my 16 month old Yellow Lab Apoquel for her allergy skin issues yesterday. Consider the risks and benefits of treatment in dogs with a history of recurrence of these conditions. I have used Benadryl for big flare ups of his skin, dosing him at .5mg per lb ( I give 50lb Jessie 25mg of Benadryl at night), and Ill do it twice a day if needed. Unlike Zoetis, when you make your claims about your supplement you dont show ANY study results or statistics. Just curious? (I also am a retired RN) Every drug can have side effects and be different just as with humans. While it is not approved by the US-FDA for use in pets, veterinarians generally prescribe (Rx only) it as an extra-label drug. You chose to claim the issues were caused by Apoquel, as a scare tactic to encourage people to buy your untested and unproven to have any benefit homemade concoction of ordinary food stuff. After this it was too late for her they said she had Better safe than sorry. Wished I had read about this drug before using. She is a golden doodle and only a year and 8 months old . can respond inappropriately, and may begin attacking the After reading some other comments above, I think Im going to discontinue use of this drug. Then my other boy has high liver enzyme. This is a awful drug. People need to look at tbeir vetwhat has been tried first. He also had these side effects while taking hydroxyzine. THIS MED IS AWFUL & I SO WISHED I NEVER GAVE IT TO HIM!!!! Dr. suggested apoquel which I paid 120. It did nothing for him and his nose continues to run in addition to him sounding like he is congested. I think a class action suit against the makers of apparel is called for. As soon as spring arrived, the scratching and paw licking began. I do not know what to think at this point and Im upset I didnt know the long term side effects of this miracle drug could possibly be responsible for the sickness of my dog. He has intermittent hotspots and a rash. The US Food and Drug Administration (FDA) has not placed any time restrictions on the use of APOQUEL. The vet was sure it was her thyroid and we did all the tests and they came back negative. Working very well for paw licking, but like others, he has to pee all the time and did so in the house yesterday (something he NEVER does). The first day I thought he had something stuck in his throat but since then it hasnt stopped so here I am I decided to look up the side effects and found this site. Such as, what is the correct hydroxyzine dosage for dogs? First, make sure to give the proper dosage based on your dogs weight. I was never told this drug is an immunosuppressent. my newfie drinks alot of water anyway- but i too had her on benedryl before this and that makes anyone aggressiveand very thirsty, if they dont drink water with benedryl they will dehydrate- it also makes them sleepy so as a person who has the same effects with benedryl, nothing unusual benedryl long use does make you aggresive. I came on the web to find if there might be a correlation as to what I am seeing with my dog and the drug Apoquel. Then came the motor coordination hiccups. I cant wait to see what the blood work will reveal though, it will be interesting. Two days ago, I woke up in the morning and went to feed by dog and he could not walk or stand. I watch the Zeljanz commercial which is basically a very similar drug for humans.listening to all the huge long list of potential side effects.cancers have happened and they say it like potential for thunderstormslike no big deal. We stopped Apoquel today because Alk phos is very high on last two tests. After reading all the comments, I have decided not to take the risk of harming my dog more by this drug. And one last comment, you claim that Other veterinarians may have their short comings, but at least they are more concerned about their patients and less about their wallets. My English bulldogs vet (different vet from Philippe) also prescribed Apoquel and it works for her. I know my Dog, . This itchiness is known as pruritus.. There are also no drug Apoquel alternatives for dogs that are effective and safe. After two trips to the vet, then being referred to a specialists, we learned his liver enzymes were off the charts. If you've a medium or small-sized pup the . The first 30 days there seemed to be no side effects, his appetite was good and it stopped the itching immediately upon the first dose he received. After allergy, blood and urine tests she put him on Apoquel, 2 times a day for 1 week and then one pill in morning. Well then..we wont be friends. please do not give your pets this drug. The gagging, a horrible sound as if he had just ate straw or something outrageously dry. I should have ask questions I usually do. I am using my supplements with lactobacillus and bifidobacterium, but you can dose lactobacillus at 1/4 capsule per 10 lbs of body weight twice daily. I have her now on a strict diet with premium dog food from Four Friends and Ropodog and the situation has much improved. Some medications may interact with . Its been 2yrs of no Atopica. A lot of dog owners are asking how much Apoquel their dog can take. Hamish is very threadbare and I have been loathed to clip him. My 12 1/2 yr old westie has been very healthy for his whole life until last august . Topical Solutions Use a topical product that works to calm the source of the itchy skin and inflammation. Labrador Retriever. At the beginning of Spring of this year. And only started happening when she went back on the drug. They were both prescribed Apoquell July 2016 over the next few months one dog developed two small growths on his feet that were removed and one found to be malignant the other benign. I have had her since she was 6 mths old and she is now an old lady at 13. Full Year 2014 Revenue of $4.8 Billion Increased 5%; Adjusted Net Income of $790 Million, or Adjusted Diluted EPS1 of $1.57, Increased 11% The reports of the studies list everything that the animals in the studies had while in the study, but a causative relationship cannot be made, merely an association. Shame on me for not doing my research. Any one with me? There are a few things to keep in mind when giving your dog either of these medications, however. We have 4 dogs, 2 cats and birds so we have used many drugs. Am going to phone my vet in the morning and get their opinion. The vitamins actually made him strong not to get the seasonal allergies so bad. She is 92# and 4 years old now so she takes 1 1/2 tabs of 16 mg daily. The Vitamin C dose is 100mg per 10lbs twice daily. Apoquel suppressed her immune system and allowed a serious infection to start that has resulted in severe diskospondylitis. Apoquel can be used along with: antibiotics antifungals anti-arthritis drugs Gabapentin should start to take effect fairly quickly, and relief should be noticed within one or two hours of administration. She said he would sleep it off. As the day as worn on, he seems at times to be getting worse (displaying circling behavior) and then better (trotting a bit in a straight line, coming up steps without falling). The new vet recommended apoquel after a while he claimed it had zero side effects and many of his patients said it was a miracle drug. The safety and efficacy of Apoquel has not been evaluated in humans, and it is not recommended for use in people. He is now experiencing tremors all over and weakness/pain in the front legs. A little research showed that the Rx was twice the recommended amount for her. I noticed she didnt seem as spunky after a week or so. If you want to help call: Roger 586-343-9003 Our otherwise healthy 4 year old Airedale Terrier has been on and off Apoquel for the last year to help her skin allergies. I forgot you add the above food mix to 3kg of chicken or turkey mince. Let him know that I would never give this precious dog any medication without our friends permission. The vet recommended apoquel. Thank you Dr. and for the shared testemoniesI assumed their were possible side effects but I think every dog reacts differently. If these sort of dermatologic/parasitic overgrowths occurred in humans from treatment with JK inhibitors, it would certainly prompt the FDA to take action to protect the patient population utilizing these medications from these severe adverse events There are a few things youll want to know before giving this to your dog. He suffers from allergies also. After about a month, he began itching again, and it got steadily worse. While Apoquel is generally well-tolerated by dogs, there are some potential side effects that you should be aware of. The vet could not detect what was wrong with her so this means a whole lot of blood test. Fourth Quarter 2014 Revenue of $1.3 Billion Increased 5% Compared to Fourth Quarter 2013 A blinded, randomized, placebo-controlled trial of the efficacy and safety of the Janus kinase inhibitor oclacitinib (Apoquel) in client-owned dogs with atopic dermatitis. My dog was given this because it was said to work faster. My 7 year old Dachshund was seen my a vet for allergies that caused her ears to itch severly. I would strongly recommend considering other avenues besides Apoquel. But I love my dogs and if this is what happens with using Apoquel. A small study of 299 dogs- 50% of the dogs took the placebo medication, and most dropped out of the study. We had a lovely dog who frequently got ear infections and because of this drug we have no dog. It is just like our medication do you honestly think the side effects are listed for us ? In that time she had two months worth of the drug. Ever since this move, my dog is itching & scratching often. And Univ of Iowa is now under clinical trial for past 4 years. We give her oatmeal baths and it dont help. An OTC alternative might be Benadryl for your dog. Metacam with known renal and liver side effects. Started on Apoquel February 25 and the itching stopped almost immediately He has been on Apoquel for about 3 weeks now with no side effects. ..for a few weeks. I have three Shih Tzu on Apoquel for three months. In fact, antihistamines are quite often used to treat skin allergies in dogs. She almost immediately stopped itching and I was delighted. Please, please be very cautious when using this drug on your babies.. Our dog Aries who is now 12 years old suffered with severe itching and allergic type reactions that appeared to start in 2016. Go ahead with apoquel. Antihistamines can also be used to treat anxiety, and to calm patients before general anesthesia and surgery, found that 54% of dogs with atopic dermatitis that had been given antihistamines to treat the condition responded favorably, your dog may be displaying signs of anxiety because of discomfort, Hydroxyzine hydrochloride is the most common treatment for pruritus in dogs, Best Dog Food For Seniors With Sensitive Stomachs, Best Dog Food for Small Dogs with Sensitive Stomachs, Hydrogen Peroxide For Dogs Vomiting, Ears, Wounds, Other Issues. I noticed she had to see alot, but only thought she was marking her spots. While still within reference ranges, mean serum globulin and mean white blood cell, My jack russel x has been on apoquel for only a few weeks but has quickly developed what looks like a fast growing tumour under his shoulder, do you think this could be related? She died in my arms on the way to the vet.My Zoey is gone and I am heart broken. Not sure! We have a rescue dog, 3 yrs old now. I cant say enough how appreciative I am this drug came along! esophagus to close keeping it enlarged (side effect). Thank you all for comments. It has been the Apoquel doing all of this, I believe. You can use a Natural flea spray that has cedarwood oil, and a safe holistic powder for putting in the cracks and crevices of your house called Borax. it may even exacerbate cancer, Diarrhea, vomiting, (both w/ If Zoetis produces the vaccines that were usedwell that would truly answer a lot of questions. I dont think so.. dont use this drug! Then Vet encouraged us to continue every 2nd day which we did. The treatment can be very effective. Makes me nervous.. At first I was like, Im worried now But its a bit of a scare tactic. Other veterinarians may have their short comings, but at least they are more concerned about their patients and less about their wallets. Im not continuing the apoquel! Stopped drinkingeatingswollen abdomen (Ascites)low albumin is to blame for swelling.proteinuriadiagnosis of Protein Losing Nephropathy. Our dog scratches till she has raw sores on her stomach underarms and other I am grateful for tis kind of forum to be able to figure out what is wrong with our dog. Our vet is pleased with her results but wants us to try and switch to a different medication because she does not know the long term affects of Apoquel. I read all the side effects from the study and didnt know what to do.

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